Figure 3.
Figure 3. Single channel conductance is not modified by the stoichiometry of ILT subunits. (A) Representative traces of single channel activity measured in an oocyte expressing Shaker ILT at +50 mV (left) and −90 mV (right). The closed and open channel current levels are indicated as c and o, respectively. (B) All point histograms of single channel group of selected traces at +50 mV (left) and −90 mV (right). (C) Single channel current amplitude versus voltage relationship for the heterotetramers and Shaker ILT. Shaker ILT (open diamonds, n = 4), 3ILT/1wt (green down triangles, n = 3), 2ILT/2wt (blue up triangles, n = 3), and 1ILT/3wt (red circles, n = 3). The internal and external (pipette) solutions both contained 120 mM K+. Patch-clamp experiment.

Single channel conductance is not modified by the stoichiometry of ILT subunits. (A) Representative traces of single channel activity measured in an oocyte expressing Shaker ILT at +50 mV (left) and −90 mV (right). The closed and open channel current levels are indicated as c and o, respectively. (B) All point histograms of single channel group of selected traces at +50 mV (left) and −90 mV (right). (C) Single channel current amplitude versus voltage relationship for the heterotetramers and Shaker ILT. Shaker ILT (open diamonds, n = 4), 3ILT/1wt (green down triangles, n = 3), 2ILT/2wt (blue up triangles, n = 3), and 1ILT/3wt (red circles, n = 3). The internal and external (pipette) solutions both contained 120 mM K+. Patch-clamp experiment.

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