Structural analyses of the RBD-Cv2.3235 and RBD-Cv2.6264 complexes. (A) Crystal structure of the complex formed by the RBD and Cv2.3235 Fab (PDB ID: 7QF0). The RBD is represented in cartoon with a transparent gray surface, highlighting the RBM (yellow), and residues that are mutated in the VOCs (red). (B) Same as in A but for the RBD-Cv2.6264 complex (PDB ID: 7QF1). (C) Polar interactions (dashed lines) formed at the interface of the RBD-Cv2.3235 complex. For simplicity, only the interactions that involve side chains on both proteins are represented. (D) Same as in C but for the RBD-Cv2.6264 complex.