Figure 5.
Figure 5. The PKA inhibitor, H-89, blocks potentiation of UTP-evoked exocytosis. (A) Representative recording of oscillating [Ca2+]i increases induced by 2 μM UTP (green line). (B) Average normalized rate of exocytosis (black circles) evoked by 1 μM FSK plus 2 μM UTP in the presence of 30 μM H-89 (n = 9). Red dotted line from Fig. 3 B shows the exocytotic response to FSK and UTP without H-89.

The PKA inhibitor, H-89, blocks potentiation of UTP-evoked exocytosis. (A) Representative recording of oscillating [Ca2+]i increases induced by 2 μM UTP (green line). (B) Average normalized rate of exocytosis (black circles) evoked by 1 μM FSK plus 2 μM UTP in the presence of 30 μM H-89 (n = 9). Red dotted line from Fig. 3 B shows the exocytotic response to FSK and UTP without H-89.

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