Figure 3.
Mgi modulation of VDI of L-type calcium current from mouse ventricular myocytes. (A) Comparison of VDI with Ca2+ versus Na+ as charge carrier. Normalized and averaged current traces for Ca2+ ICa,L(Ca) (n = 6) and Na+ ICa,L(Na) (n = 9). (B) Effect of Mgi on the inactivation of ICa,L(Na). Normalized average current traces are shown. (C) Plot of r300 versus Mgi concentrations. n = 4, 9, 13, and 10 for 0.26, 0.8, 2.4, and 7.2 mM Mgi, respectively.