Figure 5. Voltage-dependent kinetics of... | Rockefeller University Press

Figure 5.

$Figure 5. Voltage-dependent kinetics of VG currents mediated by hemichannels in a type II taste cell. (A) VG currents recorded at different voltages were fitted (•) with Eq. 15. (B) Normalized steady-state conductance Gs/Gmax versus membrane voltage. For given voltage, Gs (▵) was obtained by fitting a corresponding current trace with Eq. 15. To compare different experiments, Gs was normalized to the maximal conductance Gmax obtained for a given cell. The solid line corresponds to Eq. 16 with Vg = 31 mV and \batchmode \documentclass[fleqn,10pt,legalpaper]{article} \usepackage{amssymb} \usepackage{amsfonts} \usepackage{amsmath} \pagestyle{empty} \begin{document} $V_{g0}$ \end{document} = 11 mV. (C) Tail currents (continuous lines) were approximated with Eq. 17 (•). (D) Potential dependence of the characteristic time of activation (▾) and deactivation (▪) of VG currents. The thick and thin lines correspond to Eqs. 18 and 19, respectively. In all cases, the recording conditions were as in Fig. 1. In B and D, the data are presented as a mean ± SD (n = 7).$

Voltage-dependent kinetics of VG currents mediated by hemichannels in a type II taste cell. (A) VG currents recorded at different voltages were fitted (•) with Eq. 15. (B) Normalized steady-state conductance G_s/G_max versus membrane voltage. For given voltage, G_s (▵) was obtained by fitting a corresponding current trace with Eq. 15. To compare different experiments, G_s was normalized to the maximal conductance G_max obtained for a given cell. The solid line corresponds to Eq. 16 with V_g = 31 mV and

$V_{g0}$

= 11 mV. (C) Tail currents (continuous lines) were approximated with Eq. 17 (•). (D) Potential dependence of the characteristic time of activation (▾) and deactivation (▪) of VG currents. The thick and thin lines correspond to Eqs. 18 and 19, respectively. In all cases, the recording conditions were as in Fig. 1. In B and D, the data are presented as a mean ± SD (n = 7).

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