Figure 5.
![Figure 5. P2Y1 receptors are expressed in smaller neurons with somal diameter ≤ 10 μm (A) but are absent in larger neurons (B). (C) Inhibition of GABA receptors with 1 μM picrotoxin enhanced the SCO, and application of 100 μM ATP efficiently inhibited the SCO. Data shown are for five neurons in a typical experiment repeated three times. 100 μM ATP (D) or 30 μM UTP (E) induced large [Ca2+]i response in astrocytes that was coincident with SCO inhibition in neurons. The data shown are from neurons and astrocytes in the same field in a typical experiment.](https://cdn.rupress.org/rup/content_public/journal/jgp/132/3/10.1085_jgp.200810043/5/jgp_200810043rr_rgb_fig5.jpeg?Expires=1767947945&Signature=wEz3oiUyTNzf0uvYfyBdDkphTEUjTikEwFBt1ZEI9Z5AixqppHgczQZ19hVIprm0oC~e~-5Hge1uJybsv3IJzsaZH3mEs7-SPKj8tYQXpZPCE5g-CBMM2tP-MO8rAeLks7f8Ebjdo7qichYmPLsdsDDiFcJoQEcL2LK7~2uXNGVC6TnTJ3d~nColfcRVvOL9icnea~nDhq5UHq2RsQR-tByvluLlMhauTcsO4em6cR5XouJwAVGAWsuTqVPIuwtYIxEz4O5aQXbKwH5hYdOdFLn2zQppuODKTX-OxFnm6NOKhWmDW01iDRCdA3rFHHNnNC47PIPh6rfUR8Wubf8-Kg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
P2Y1 receptors are expressed in smaller neurons with somal diameter ≤ 10 μm (A) but are absent in larger neurons (B). (C) Inhibition of GABA receptors with 1 μM picrotoxin enhanced the SCO, and application of 100 μM ATP efficiently inhibited the SCO. Data shown are for five neurons in a typical experiment repeated three times. 100 μM ATP (D) or 30 μM UTP (E) induced large [Ca2+]i response in astrocytes that was coincident with SCO inhibition in neurons. The data shown are from neurons and astrocytes in the same field in a typical experiment.
