Composition of the dwell-time distribution of all intervals for Scheme 2 in which k_C2-C1 is 5,000/s, giving a t_C2/t_C1 ratio of 0.2. See legend of Fig. 3 for plot details. Compared with Fig. 3 where the t_C2/t_C1 ratio 1, decreasing t_C2/t_C1 fivefold greatly increases the number of {C₁} intervals needed to fill in the gap between {C₁C₂} and E2 to complete E₂ (gray areas in C and D and plot in E). Consequently, most of the {C₁} intervals go to E₂, leaving very few {C₁} intervals to generate E₁. The net result is that E₁ has a low magnitude and fast time constant (A–C).