Post-transplant thymopoietic recovery of conventional αβT cells occurs independently of thymus medulla regeneration. (A) CD4/CD8 profiles of thymocytes from control or BMT mice at the indicated time points, the latter pregated on donor CD45.1+ cells. d, day. (B) Quantitation of CD4+CD8+ and conventional CD25−Foxp3− (cSP) CD4+TCRβ+/CD8+TCRβ+ thymocytes at indicated time points in control (white dots) and BMT mice (black dots). (C and D) Subdivision of cSP CD4+TCRβ+ thymocytes into immature CD69+CD62L− and mature CD69−CD62L+ subsets; quantitation of control (white dots) and BMT mice (black dots) is in D. All data from three separate experiments; n = 8 for each time point. Error bars indicate SEM; *, P < 0.05; **, P < 0.01; ****, P < 0.0001.