Figure 5.
Characterization of Ago2 binding in Δ or flox B cells stimulated with anti-CD40, IL-4, IL-21. (A) Annotations and relative coverage of reads from each of the Δ and flox B cell libraries aligning to annotated mRNA sequences (left) and noncoding RNA sequences (right) averaged from four libraries for each genotype. snoRNA, small nucleolar RNA. (B) Distribution of miRNA and non-miRNA reads in each library. (C) Mean analysis plot for miRNA reads only. Mean miRNA read count versus log10 miRNA read count per million of flox versus Δ reads. Red dots are differentially captured miRNAs by DESeq2 with false discovery rate <0.05.