Figure 8. The effect of 17AAG on temporal lobe epileptogenesis. (A) Experimental design. 24 h after KA-induced SE, mice were injected with 17AAG once every other day for 2 wk; littermate WT mice were injected with DMSO. Thereafter, mice were implanted with electrodes and followed for 2 wk using vEEG recording without drug intervention. (B) Statistical analysis of the total number of seizures in the two recording weeks (n = 18 mice per group; *, P < 0.05, Student’s t test). Data are combined from two independent experiments.
Figure 8.

The effect of 17AAG on temporal lobe epileptogenesis. (A) Experimental design. 24 h after KA-induced SE, mice were injected with 17AAG once every other day for 2 wk; littermate WT mice were injected with DMSO. Thereafter, mice were implanted with electrodes and followed for 2 wk using vEEG recording without drug intervention. (B) Statistical analysis of the total number of seizures in the two recording weeks (n = 18 mice per group; *, P < 0.05, Student’s t test). Data are combined from two independent experiments.

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