Hypercytokinemia in STING N153S mice. (A–P) Serum was collected from 4–6-mo-old STING N153S and WT littermate control mice, and cytokine and chemokine levels were measured by Bio-Plex assay (n = 9 mice per group). Data represent the mean from two independent experiments. *, P < 0.05; **, P < 0.005 by Mann–Whitney.