TMEM16F is the dominant scramblase in T cells. (A) Immunoblot analysis of TMEM16F expression in WT or TMEM16F-deficient (KO) thymocytes. (B) PS exposure was examined by Annexin V staining and flow cytometry on splenocytes from TMEM16F-KO or WT mice in response to calcium ionophore A23187. DMSO was used as control. B220, B cells. Data are representative of at least two independent experiments.