Figure 2.
Figure 2. G9a-deficient mice lack tissue ILC2s. (A) Frequencies of ILC2s in the mLN, lung, and VAT of G9afl/fl and Vav.G9a−/− mice. ICOS, inducible T cell co-stimulator. (B) Quantification of total ILC2s (mLN, n = 9–10; and lung, n = 6) or frequency of live CD45+ (VAT, n = 4). (C) Representative expression of ST2 in mature ILC2s from G9afl/fl (dark gray) and Vav.G9a−/− mice (black line). Light gray represents the negative control (Ctrl). *, P < 0.05; Student’s t test. Errors bars indicate SEM.

G9a-deficient mice lack tissue ILC2s. (A) Frequencies of ILC2s in the mLN, lung, and VAT of G9afl/fl and Vav.G9a−/− mice. ICOS, inducible T cell co-stimulator. (B) Quantification of total ILC2s (mLN, n = 9–10; and lung, n = 6) or frequency of live CD45+ (VAT, n = 4). (C) Representative expression of ST2 in mature ILC2s from G9afl/fl (dark gray) and Vav.G9a−/− mice (black line). Light gray represents the negative control (Ctrl). *, P < 0.05; Student’s t test. Errors bars indicate SEM.

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