Potential points of intervention in the preerythrocytic stages of the Plasmodium life cycle. (1) Frevert et al., 1996; Coppi et al., 2007; (2) Mota et al., 2002; Cha et al., 2015; (3) Yalaoui et al., 2008; Foquet et al., 2015; (4) Liehl et al., 2014; (5) Epiphanio et al., 2008; Sinnis and Ernst, 2008; (6) Prado et al., 2015.