Figure 1.
Phenotype and morphology of IFN-DCs and SLE-DCs. (A) Surface phenotype of IFN-DCs and SLE-DCs. Closed gray histograms indicate isotype control, and black line histograms indicate markers of interest. (B) Summarized data (mean ± SD in A) for CD1a, CCR5, and CD163 expression. Student’s t test: **, P < 0.01. (C) Giemsa staining of IFN-DCs and SLE-DCs generated with sera from SLE patients. Bars, 2.5 µm. In A and C, experiments using sera from 20 SLE patients and monocytes from 12 healthy donors showed similar results.