The pI of CDR regions of mouse and human L chains. Mouse and human L chains are plotted in order of increasing CDR pI. CDRs are identified according to the Kabat definition. Mouse editor and human putative editor L chain CDR pI values are shown in solid blocks and these L chains are labeled on the X axis. The pI values for the remaining L chains are shown as open data points to place the editors in context within the full set of L chains in mouse and in human.