Model of mimotope-2 in the peptide-binding groove of HLA-DP2. The amino acids of mimotope-2 were introduced into the peptide of the HLA-DP2–pDRa structure (Protein Data Bank accession no. 3LQZ) using Swiss PDB Viewer 4.0. Rotamers of the amino acids of mimotope-2 that avoided conflict with the structure were selected. Ribbon representations of DP2 α (cyan)- and DP2 β (magenta)-chains are shown. Wireframe representations of the side chains of mimotope-2, βGlu26, βGlu68, and βGlu69 with CPK coloring are shown.