Figure 2.
Figure 2. T cell–intrinsic requirement for G9a in immunity to T. muris. G9afl/fl and G9aΔT mice were infected with T. muris and sacrificed 21 d later. (A) mLN cells were restimulated with T. muris antigen for 72 h and analyzed by ELISA for production of IFN-γ and IL-4. (B) T. muris–specific IgG1 and IgG2a levels in the serum of infected G9afl/fl and G9aΔT mice were determined by ELISA. (C) Worm burdens (number of worms per animal) were determined microscopically. Data are representative of two independent experiments (n = 10). Asterisks indicate P < 0.05. Error bars indicate SEM.

T cell–intrinsic requirement for G9a in immunity to T. muris. G9afl/fl and G9aΔT mice were infected with T. muris and sacrificed 21 d later. (A) mLN cells were restimulated with T. muris antigen for 72 h and analyzed by ELISA for production of IFN-γ and IL-4. (B) T. muris–specific IgG1 and IgG2a levels in the serum of infected G9afl/fl and G9aΔT mice were determined by ELISA. (C) Worm burdens (number of worms per animal) were determined microscopically. Data are representative of two independent experiments (n = 10). Asterisks indicate P < 0.05. Error bars indicate SEM.

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