Figure 2.
Survival of IκBβ−/− mice after high-dose LPS challenge. Survival curves of IκBβ−/−, IκBβ+/−, and WT mice after the injection of LPS (30 mg/kg). Kaplan-Meier analysis demonstrated a significant difference in survival between IκBβ−/− and WT (log-rank test IκBβ−/− versus WT; P < 0.0001). Data are from three separate experiments and the number of mice in each group is indicated.