Roles of IL-25, IL-33, and TSLP in skin swelling and inflammation and ILC2 infiltration in BALB/c mice strains. MC903 or vehicle was applied topically for 4 d to the ear of wild-type or knockout mice as indicated. Increase (percent) in ear thickness (A), total LN cell number (LN; B), number of ILC2 in the ear sample (C), and number of ILC2 in the LN (D) were documented. n = 9 –10 per group. Data are representative of two independent experiments. *, P < 0.05; **, P < 0.01; ***, P < 0.001, unpaired Student’s t test with Welch’s correction (mean and SEM).