Figure 4.
TLR1 also contributes to trafficking of CD11c+ cells during oral but not i.v. infection. TLR1+/− and TLR1−/− mice were infected with 105 Y. enterocolitica. (A) MLNs were harvested 3 d after oral infection, and flow cytometry was performed to examine the percentage (left panels) and total cell number (right panel) of CD11c+ cells. Cells were gated on FSC and SSC and CD45. (B) SPLs were harvested 3 d after i.v. infection, and flow cytometry was performed as described in A. Data are pooled from two individual experiments (n = 6). Horizontal bars represent the mean. *, P < 0.05; **, P < 0.01 (unpaired Student’s t test).
