TLR3-mediated IFN production is normal in P2’s fibroblasts. (a and b) WT (C+), P2, UNC-93B^−/−, and NEMO^−/− fibroblasts were stimulated with various doses of poly(I:C) for 24 h. The production of IFN-β (a) and IFN-λ (b) was assessed by ELISA. The graphs show the mean values ± SD for three independent experiments. NS, nonstimulated.