Figure 4.

TFF2 promotes spontaneous expulsion and termination of egg production during N. brasiliensis infection. (A) N. brasiliensis intestinal worm numbers recovered from WT versus TFF2−/− mice at the indicated time points after a primary infection. Means ± SE of 8–10 mice/group are shown. n.d., not detected. (B) N. brasiliensis fecal egg numbers in WT versus TFF2−/− mice after a primary infection. Means ± SE of 8–10 mice/group are shown. (C) Immunostaining for Tff2 protein (magenta precipitate indicated by arrows) in paraffin-embedded sections of jejunum from N. brasiliensis–infected WT (top) or TFF2−/− (bottom) mice at day 7 after infection. Bars, 70 µm. Data are representative of four independent experiments (*, P < 0.05; **, P < 0.01).

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