Figure 9. Infarct size is reduced in p75NTR deficient mice 10 d after I-R surgery. (A) Representative picture of a 1-mm heart section showing the area at risk determined by re-ligation of the left anterior coronary artery 10 d after surgery and perfusion with Evans blue dye. The area at risk is devoid of blue dye. (B) Representative picture of a Masson’s trichrome stain to identify the infarcted region of the heart (0.5 mm) 10 d after surgery. (C) The area at risk (percentage of total ventricular volume), determined by perfusion with Evans blue dye in p75−/− mice compared with wild-type mice. (D) Infarct size normalized to the area at risk in p75−/− mice compared with wild-type 10 d after I-R surgery. **, P < 0.01, mean ± SEM, n = 5–6 mice/genotype. Bars: (A) 1 mm; (B) 0.5 mm.
Figure 9.

Infarct size is reduced in p75NTR deficient mice 10 d after I-R surgery. (A) Representative picture of a 1-mm heart section showing the area at risk determined by re-ligation of the left anterior coronary artery 10 d after surgery and perfusion with Evans blue dye. The area at risk is devoid of blue dye. (B) Representative picture of a Masson’s trichrome stain to identify the infarcted region of the heart (0.5 mm) 10 d after surgery. (C) The area at risk (percentage of total ventricular volume), determined by perfusion with Evans blue dye in p75−/− mice compared with wild-type mice. (D) Infarct size normalized to the area at risk in p75−/− mice compared with wild-type 10 d after I-R surgery. **, P < 0.01, mean ± SEM, n = 5–6 mice/genotype. Bars: (A) 1 mm; (B) 0.5 mm.

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