Figure 2.
p75NTR and SorCS2, to which proNGF also binds, are up-regulated in PDGFR-β+ pericytes after I-R in mice. (A) Immunoprecipitation–Western blot analysis from 293T cells transfected with the indicated plasmids. The experiment was performed three independent times. (B) p75NTR (red) expression on PDGFR-β+ (green) pericytes in the peri-infarct regions of injured hearts compared with pericytes of uninjured myocardium. (C) SorCS2 (red) expression in a population of pericytes coexpressing PDGFR-β (green) in the injured myocardium after I-R. (B and C) Bar, 25 µm. n = 3 mice/group.