Figure 1.

RAG2−/−x γc−/− mice are more susceptible to MCA-induced sarcomas than syngeneic RAG2−/− and WT mice. The indicated dose of MCA was injected into the subcutaneous space of mice, and sarcoma formation was monitored over time. All cohorts consisted of 20 mice. Tumor-positive mice were defined as those that harbored a progressively growing mass ≥25 mm2. Similar results were found in a repeat experiment that included the 5 and 25 µg doses.

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