Expression levels of genes involved in lipid trafficking and metabolism in the brains of Tg19959 mice and WT littermates treated with and without HP-β-CD. (A–G) Relative expression levels of mRNAs normalized to the levels of actin. n = 7–10 in each group. *, P < 0.05; **, P < 0.01. All results were obtained and analyzed from two separate animal studies. (H and I) Representative Western blots of NPC1 and ABCA1 compared with tubulin in the brains of Tg19959 mice treated with and without HP-β-CD.