Figure 1.
γc and IL-7Rα expression on thymocytes from wild-type and cKO mice. (Top) Schematic of CD4Cre and E8IIICre expression in developing thymocytes. Surface expression of γc (middle) and IL-7Rα (bottom) was determined on thymocytes from WT (Cre−) or cKO (Cre+) mice using CD4Cre (colored dashed lines) or E8IIICre (colored solid lines). Total thymocytes were stained for CD4, CD8α, TCR-β, and γc or IL-7Rα and gated on the indicated thymocyte populations. MFI of γc and IL-7Rα staining are shown. Data are representative of four independent experiments.