Figure 6.
Figure 6. IL-20R1 deficiency protected mice from OVX-induced bone loss. (A) Micro-CT analysis of the right tibias of IL-20R1+/+, IL-20R1+/−, and IL-20R1−/− mice 2 mo after OVX treatment (n = 5/group). Data are representative of three independent experiments. (B) BMD in the tibias of OVX mice. Values are means ± SD of five mice. Data are representative of three independent experiments. (C and D) The number of osteoclasts (C) and osteoclast areas (D) per bone surface in TRAP-stained sections. N.Oc/BS, number of osteoclasts per bone surface; Oc.S/BS, osteoclast surface per bone surface (n = 5). Values are means ± SD of five mice. Data are representative of three independent experiments. *, P < 0.05 versus corresponding sham-operated mice; #, P < 0.05 versus OVX-IL-20R1+/+ mice.

IL-20R1 deficiency protected mice from OVX-induced bone loss. (A) Micro-CT analysis of the right tibias of IL-20R1+/+, IL-20R1+/−, and IL-20R1−/− mice 2 mo after OVX treatment (n = 5/group). Data are representative of three independent experiments. (B) BMD in the tibias of OVX mice. Values are means ± SD of five mice. Data are representative of three independent experiments. (C and D) The number of osteoclasts (C) and osteoclast areas (D) per bone surface in TRAP-stained sections. N.Oc/BS, number of osteoclasts per bone surface; Oc.S/BS, osteoclast surface per bone surface (n = 5). Values are means ± SD of five mice. Data are representative of three independent experiments. *, P < 0.05 versus corresponding sham-operated mice; #, P < 0.05 versus OVX-IL-20R1+/+ mice.

This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal