CL1-R2 inhibits FGF2-induced rabbit corneal neoangiogenesis. (A) Representative photographs of corneas treated with control IgG1 (Ctrl) or CL1-R2 mAb. Neovascularization was assessed 8 d after corneal grafting of FGF2-containing implants. Arrows, implants; arrowhead, neovessels. Bar, 2 mm. (B) Quantitative analysis of neovascularization in Ctrl- or CL1-R2–treated corneas. Values are means ± SEM obtained from four independent experiments, n = 5 rabbits/group/experiment. ***, P < 0.0001 (Mann-Whitney U test).