CD36 on macrophages regulates the lymphangiogenic response in the cornea. (A) The macrophage marker CD11b (green) and the TSP-1 receptor CD36 (red) are colocalized (yellow) on monocytic cells in the normal corneal stroma. (B) The specific lymphatic marker LYVE-1 (red) is not colocalized with antibodies against CD36 (green), and is expressed by blood vessels detectable at the limbus. (C) Morphometric comparison of corneal lymphvascularized area between WT (n = 8) control and CD36^−/− (n = 9) mice (reconstituted with WT bone marrow) in a mouse model of inflammatory corneal neovascularization. Error bars indicate SD.