Figure 2.
Effective control of MCMV proliferation in BALB mice depends on the H-2 haplotype. (A) BALB.By (H-2b), BALB/c (H-2d), and BALB.K (H-2k) mice were infected with either 2.5 × 103 PFU/mouse (BALB.By) or 5 × 103 PFU/mouse (BALB/c and BALB.K) of MCMV. Viral titers were assessed in the spleen at days 2, 4, 6, and 10 p.i. (B) Day-4 viral titers in the spleen and liver of BALB.By and BALB.K mice infected with 2.5 × 103 PFU/animal are shown. The data are presented as median viral titer ± interquartile range (IQR). The number of animals used at each time point is between 4 and 12 and represents four pooled experiments.