Immune and genetic correlates of vaccine-mediated protective immunity. (A and B) Sera (A) and tear (B) IgG and IgA antibody titer–specific A2497 organisms were measured by ELISA (n = 2). Error bars show the standard deviation of the tear antibody titers measured in the left and the right eyes. (C) Serum-neutralizing antibody titers against A2497 organisms. Percentage of specific neutralization for each dilution was calculated as [(preimmune IFUs − immune IFUs)/preimmune IFUs] × 100. (D) MHC class I and II alleles of immunized monkeys. In A–C, results are shown for one of two independent experiments.