Figure 3. Repeated infections of nonhuman primates with the plasmid-deficient A2497Pāˆ’ strain do not cause ocular pathology. RML 145, 641, and 642 were reinfected at weeks 10 and 18. RML 643, 647, and 147 were reinfected at weeks 5 and 8 (individual data points are plotted). Day 0 indicates the time of the first infection of each animal. Arrows indicate the time of the reinfections. Chlamydial burden is the geometric mean of recoverable IFU for both eyes of individual monkeys monitored by culture from conjunctival swabs. Clinical disease score is the aggregate clinical score (hyperemia and follicle formation) for both eyes of individual monkeys. The experiment was done once.
Figure 3.

Repeated infections of nonhuman primates with the plasmid-deficient A2497Pāˆ’ strain do not cause ocular pathology. RML 145, 641, and 642 were reinfected at weeks 10 and 18. RML 643, 647, and 147 were reinfected at weeks 5 and 8 (individual data points are plotted). Day 0 indicates the time of the first infection of each animal. Arrows indicate the time of the reinfections. Chlamydial burden is the geometric mean of recoverable IFU for both eyes of individual monkeys monitored by culture from conjunctival swabs. Clinical disease score is the aggregate clinical score (hyperemia and follicle formation) for both eyes of individual monkeys. The experiment was done once.

This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal