Bcl11b^F/F/CD4-Cre mice show abnormal up-regulation of the gut-homing markers in T cells. (A) Frequencies of CD4⁺ T cells expressing the gut-homing markers α4β7 integrin and CCR9 in the mLNs and spleen of Bcl11b^F/F/CD4-Cre and WT mice. (B) Frequencies of α4β7 integrin and CD44-expressing CD4 single-positive and DP thymocytes in Bcl11b^F/F/CD4-Cre and WT mice. (A and B) Data are representative of at least three pairs of mice. (C) Fold change in mRNA levels for α4β7 integrins and CD44 in DP thymocytes from Bcl11b^F/F/CD4-Cre mice. Data are representative of two independent microarrays.