Figure 2.
Figure 2. HCDR3 sequences for clones subjected to mutation-reversion analysis. Germline-encoded DH sequences are shown above and germline-encoded VH and JH sequences are shown below hybridoma (shaded) sequences. Somatic mutations are underlined. The blue lowercase t in J6.1 is a templated nucleotide (P element) added during VH(D)JH recombination. In lineage #4, somatic mutations that eliminated Arg codons are explicitly indicated for both members.

HCDR3 sequences for clones subjected to mutation-reversion analysis. Germline-encoded DH sequences are shown above and germline-encoded VH and JH sequences are shown below hybridoma (shaded) sequences. Somatic mutations are underlined. The blue lowercase t in J6.1 is a templated nucleotide (P element) added during VH(D)JH recombination. In lineage #4, somatic mutations that eliminated Arg codons are explicitly indicated for both members.

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