Figure 4.
Figure 4. Non-strict coupling between ATP hydrolysis and gating cycle. Opening events of Cysless/R352C- (A) or R352C-CFTR (B) containing one (events 1, 3, and 4 in A, and 1–4 in B) or more (events 2 and 5 in A, and 5 in B) O1→O2 transitions. Events were extracted from traces in Figs. 2 B and 3 A. Chosen events were specified in boxes and numbered in Figs. 2 B and 3 A.

Non-strict coupling between ATP hydrolysis and gating cycle. Opening events of Cysless/R352C- (A) or R352C-CFTR (B) containing one (events 1, 3, and 4 in A, and 1–4 in B) or more (events 2 and 5 in A, and 5 in B) O1→O2 transitions. Events were extracted from traces in Figs. 2 B and 3 A. Chosen events were specified in boxes and numbered in Figs. 2 B and 3 A.

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