Figure 4. Rejection of the transplanted ES cybrids containing allogenic mtDNA. (A) Identification of the mtDNA genotypes of the ES cybrids. B6 and NZB represent mtDNAs from B6 and NZB mice, respectively. (B–E) Examination of tumor formation of the ES cybrids by their inoculation into B6 mice (B), B6mtNZB mice (C), B6 β2m−/− mice (D), and B6 NKRed mice (E). Similar results were obtained in two independent experiments. Error bars represent SD.
Figure 4.

Rejection of the transplanted ES cybrids containing allogenic mtDNA. (A) Identification of the mtDNA genotypes of the ES cybrids. B6 and NZB represent mtDNAs from B6 and NZB mice, respectively. (B–E) Examination of tumor formation of the ES cybrids by their inoculation into B6 mice (B), B6mtNZB mice (C), B6 β2m−/− mice (D), and B6 NKRed mice (E). Similar results were obtained in two independent experiments. Error bars represent SD.

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