Figure 4.
![Figure 4. Simulation of the pre–steady-state ON and OFF currents (solid lines) using the five-state model. The simulation is generated in the presence of (A) 90 mM, (B) 50 mM, and (C) 10 mM external Na+ concentrations ([Na+]o). Symbols represent the mean experimental data ± SEM (inset) The Q(Vm) curves corresponding to the integrals of the simulated and experimental OFF transient currents are compared at 90, 50, and 10 mM [Na+]o.](https://cdn.rupress.org/rup/content_public/journal/jgp/140/4/10.1085_jgp.201210822/4/jgp_201210822_fig4.jpeg?Expires=1767810676&Signature=eML8Aec4QKo4jMgUVzYeon5Gily7bndicHRMpmMd09jqb9gHX3jH4CNsKEoCYUvqKK1BAgNUwPYBTQ9D58do04WM-jX6N5gemNb8x6HOJ64YYAk6QpftrwDpBHnfjYx5ko9-UXNibVMGZRXHS-pcYqTmNCw9-c9n5NdB8cWLLgfyTrfs3wOqSKuWqz8t7oX~j4~MdLYpXqH9MbwoDLocAc5hCGRvdDId20rdyJ5XyDKR~aOqCX4J~XneqTE5cmeh8ua96pE2rcP7Bv3fk~uKw0DCBMjfWJfcqz1brIac~YLB2GM~DH20UrhVcqmeYTztBuNOpVlagYm3OO39KFgCoA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Simulation of the pre–steady-state ON and OFF currents (solid lines) using the five-state model. The simulation is generated in the presence of (A) 90 mM, (B) 50 mM, and (C) 10 mM external Na+ concentrations ([Na+]o). Symbols represent the mean experimental data ± SEM (inset) The Q(Vm) curves corresponding to the integrals of the simulated and experimental OFF transient currents are compared at 90, 50, and 10 mM [Na+]o.
