Loss of APJ protects mice from pathological cardiac hypertrophy secondary to transaortic constriction. (a) Hearts and (b) histological sections of hearts from mice subjected to sham surgery or transaortic constriction. WT, wild-type; APJ-KO, APJ knocked-out; TAC, transaortic constriction. Reprinted by permission from Macmillan Publishers, Ltd. Nature. 488:394–398. 2012.

Loss of APJ protects mice from pathological cardiac hypertrophy secondary to transaortic constriction. (a) Hearts and (b) histological sections of hearts from mice subjected to sham surgery or transaortic constriction. WT, wild-type; APJ-KO, APJ knocked-out; TAC, transaortic constriction. Reprinted by permission from Macmillan Publishers, Ltd. Nature. 488:394–398. 2012.

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