Figure 10.

Model calculations of the attenuation and surface and TTS components of ICl for various distributions of PCl. (A) Predicted percentage attenuation (open squares) plotted as a function of the percentage PCl in the TTS. (B) Total (solid stars), sarcolemma (solid circles, shown as % of total), and TTS (open circles, shown as % of total) chloride currents calculated for various percentages of PCl in the TTS. Note that the left ordinate axis is inverted (negative currents are drawn upward). The fiber radius was 25.5 μm; model parameters (other than PCl) were those in Tables 1 and 2 of the Appendix. Specific values of PCl (in cm/s) for the surface and TTS membranes, respectively, for every percentage distribution in the TTS (in parenthesis) were: 0 and 4.96 × 10−5 (100%); 5.05 × 10−6 and 4.55 × 10−5 (90%); 1.02 × 10−5 and 4.1 × 10−5 (80%); 1.56 × 10−5 and 3.64 × 10−5 (70%); 2.16 × 10−5 and 3.25 × 10−5 (60%); 2.78 × 10−5 and 2.78 × 10−5 (50%); 3.45 × 10−5 and 2.3 × 10−5 (40%); 4.2 × 10−5 and 1.38 × 10−5 (30%); 5.2 × 10−5 and 1.3 × 10−5 (20%); 6.66 × 10−5 and 7.4 × 10−6 (10%); 7.5 × 10−5 and 0 (0%).

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