VL diagrams show the contribution of major currents during the interburst period at 8 mM [G] (A) and 16 mM [G] (B). (Top) Time-dependent changes in VL (red) and Vm (black). The Vm trace is overlapped by VL. (Middle) Time-dependent changes in the contribution (c) of individual currents indicated with different colors. A positive c indicates that the time-dependent change in the corresponding current contributes to depolarization (in mV sā1), and vice versa. The contribution of ICaV was divided into c of dCaV and c of fus. The rest for ICaV was negligibly small (not depicted). (Bottom) Separation of the contribution of INaK into [ATP]- and [MgADP]-dependent components (dark yellow) and [Na+]i-dependent component (gray). Effects of other factors on INaK, such as time-dependent changes in [K+]i or Vm, were negligibly small (not depicted). The time scales refer to those for the gray bars in Fig. 4 (A and B).