Figure 2.
Figure 2. Ci-KCNQ1 is not properly modulated by KCNE1. (A) Representative current traces in the absence and presence of KCNE1 or KCNE3 for human KCNQ1 (hKCNQ1) and Ci-KCNQ1. The membrane potential was stepped up from −120 or −100 to 60 mV in 20-mV increments and subsequently stepped to −30 mV for tail currents. (B) G-V relationships for human KCNQ1 (top) and Ci-KCNQ1 (bottom) in the absence and presence of KCNE1 or KCNE3.

Ci-KCNQ1 is not properly modulated by KCNE1. (A) Representative current traces in the absence and presence of KCNE1 or KCNE3 for human KCNQ1 (hKCNQ1) and Ci-KCNQ1. The membrane potential was stepped up from −120 or −100 to 60 mV in 20-mV increments and subsequently stepped to −30 mV for tail currents. (B) G-V relationships for human KCNQ1 (top) and Ci-KCNQ1 (bottom) in the absence and presence of KCNE1 or KCNE3.

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