Figure 1.
![Figure 1. The Lymn-Taylor cycle (Biochemistry. 1971. 10:4617). In the absence of ADP or ATP (bottom left), the myosin head binds strongly to the actin filament (gray). ATP binding to myosin causes a rapid dissociation of the actin–myosin complex (bottom right). The subsequent hydrolysis of ATP leads to a stable myosin.ADP.Pi complex (top right) in which the head has “swung” back (ready to recombine with actin [top left]). The mechanical movement of the myosin filament relative to the actin filament occurs as ADP and Pi dissociate from the actin.myosin.ADP.Pi complex (top left to bottom left). Modified after M.A. Geeves and K.C. Holmes (1999. Annu. Rev. Biochem. 68:687).](https://cdn.rupress.org/rup/content_public/journal/jgp/119/2/10.1085_jgp.119.2.117/5/jgp8554_f1.jpeg?Expires=1767782552&Signature=XlOK2sH5QEeuiSzRA~xYbLiAPny7Kl2WotnzntfLrMAX68RK9bbYtxPZy59Q0HjfB3oxwtpu3SX3nES0hhTs22n~jm0G~Tg3P62u3ctWKkENUd-GQa6NnOUD7BIdCZvC4ANHNh3~ALfvItjeliR0ly08NZfph-afLg3nePEn0-SG0a2GHF-fnnigpyPLauBtC~5SjxcdUy75iaiDam9Vy2H9vpP98Fh87-0E4kfOyrPWwWRSa74VHNynf2ll34gSbawvzRGHAb0coqP6ataLEAh0QpMJWdletG8QhDuJoy~Z7NWqo6MTzMKLGTLY8wLsWeALM2y8Kl0nBtQN5SHPig__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
The Lymn-Taylor cycle (Biochemistry. 1971. 10:4617). In the absence of ADP or ATP (bottom left), the myosin head binds strongly to the actin filament (gray). ATP binding to myosin causes a rapid dissociation of the actin–myosin complex (bottom right). The subsequent hydrolysis of ATP leads to a stable myosin.ADP.Pi complex (top right) in which the head has “swung” back (ready to recombine with actin [top left]). The mechanical movement of the myosin filament relative to the actin filament occurs as ADP and Pi dissociate from the actin.myosin.ADP.Pi complex (top left to bottom left). Modified after M.A. Geeves and K.C. Holmes (1999. Annu. Rev. Biochem. 68:687).
