Figure S3.
SDN-1 is equally abundant at excitatory and inhibitory synapses.(A) Confocal detection and fluorescence profiles of mNG-SDN-1 and GABAARs (UNC-49-RFP) along the dorsal cord. (B) Percentage of L-AChRs and GABAARs colocalized with mNG-SDN-1, calculated using Manders’ coefficient on processed images. (C and D) Confocal detection and fluorescence profiles of mNG-SDN-1 and the presynaptic active zone marker CLA-1-BFP under the control of either the GABAergic neuron-specific promoter Punc-47 (C) or the cholinergic neuron-specific promoter Punc-17 (D). (E) Mean intensity of the mNG-SDN-1 signal at cholinergic and GABAergic synapses. Scale bars, 10 µm.

SDN-1 is equally abundant at excitatory and inhibitory synapses. (A) Confocal detection and fluorescence profiles of mNG-SDN-1 and GABAARs (UNC-49-RFP) along the dorsal cord. (B) Percentage of L-AChRs and GABAARs colocalized with mNG-SDN-1, calculated using Manders’ coefficient on processed images. (C and D) Confocal detection and fluorescence profiles of mNG-SDN-1 and the presynaptic active zone marker CLA-1-BFP under the control of either the GABAergic neuron-specific promoter Punc-47 (C) or the cholinergic neuron-specific promoter Punc-17 (D). (E) Mean intensity of the mNG-SDN-1 signal at cholinergic and GABAergic synapses. Scale bars, 10 µm.

This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal