Loss of UNC-60A mitigates recycling defects in RTKN-1–deficient cells. (A and A′) Confocal images showing the distribution of Utrophin-CH in intestinal cells. Box-and-whisker plots (n = 18 cells): 10–90th percentile; dots, outliers; red midline, median of WT; boundaries, quartiles. ***, P < 0.001 by one-way ANOVA followed by Dunn’s post hoc multiple comparison test. (B–C′) Confocal images showing the distribution of hTAC-GFP and hTfR-GFP. Box-and-whisker plots (n = 18 cells): 10–90th percentile; dots, outliers; red midline, median of WT; boundaries, quartiles. *, P < 0.05; ***, P < 0.001 by one-way ANOVA followed by Dunn’s post hoc multiple comparison test. The black asterisks in the image panels indicate intestinal lumen. Scale bars, 10 µm.
Figure 6.

Loss of UNC-60A mitigates recycling defects in RTKN-1–deficient cells. (A and A′) Confocal images showing the distribution of Utrophin-CH in intestinal cells. Box-and-whisker plots (n = 18 cells): 10–90th percentile; dots, outliers; red midline, median of WT; boundaries, quartiles. ***, P < 0.001 by one-way ANOVA followed by Dunn’s post hoc multiple comparison test. (B–C′) Confocal images showing the distribution of hTAC-GFP and hTfR-GFP. Box-and-whisker plots (n = 18 cells): 10–90th percentile; dots, outliers; red midline, median of WT; boundaries, quartiles. *, P < 0.05; ***, P < 0.001 by one-way ANOVA followed by Dunn’s post hoc multiple comparison test. The black asterisks in the image panels indicate intestinal lumen. Scale bars, 10 µm.

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