Bioinformatic analysis of SFPQ protein sequence and transport parameters of SFPQ granules in axons of DRG sensory neurons. (A) Schematic of protein domains of SFPQ and the probability score of the SFPQ sequence for being disordered and prion like as predicted by IUPred2 (top) and PLAAC (bottom), respectively. (B and C) Frequency distribution of instantaneous velocity (A) and run length (B) for Fig. 1, E and F, respectively. Data analyzed from 259 SFPQ particles, from 34 axons across four independent microfluidic experiments. IDR, intrinsically disordered region.