The role of the GET pathway in the transfer of mistargeted TA proteins from the mitochondrial OM to ER membrane. Msp1 extracts mislocalized TA proteins from the mitochondrial OM in an ATP-dependent manner. Get3 then binds to the extracted TA proteins in the cytosol and escorts them to the Get1-Get2 complex in the ER membrane. While TA proteins that failed to be captured by Get3 tend to return to the mitochondrial OM again, a fraction of them can move to the ER membrane via an uncharacterized Get-independent pathway upon Msp1 overexpression. See Discussion for details.