Figure 1.
Figure 1. Talin domain organization and interactions. (A) Talin contains an N-terminal FERM domain (F0–F3) connected via an 80-aa unstructured linker to the 13 talin rod domains R1–R13. 9 of the 13 rod domains contain VBSs (red). (B) Major binding sites for folded talin domains (black boxes) and unfolded domains (white boxes).

Talin domain organization and interactions. (A) Talin contains an N-terminal FERM domain (F0–F3) connected via an 80-aa unstructured linker to the 13 talin rod domains R1–R13. 9 of the 13 rod domains contain VBSs (red). (B) Major binding sites for folded talin domains (black boxes) and unfolded domains (white boxes).

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