Figure 7.
Microtubule-dependent movements of Dynein 1 heavy chain polysomes. (A) Movements of tagged DYNC1H1 polysomes. Legend as in Fig. 4. Bar, 6 µm. (B) Kymograph showing rapid rectilinear motions of the green particle of A. (C) Percentage of DYNC1H1 polysome displaying rapid rectilinear motion over a 4-min time period, in untreated cells (Cont) or in cells treated with cytochalasin D (CytoD) or nocodazole (Noco). The error bars represent the SD of the mean between experimental replicates (n = 3). (D and E) Comparison of the diffusion of DYNC1H1 polysomes with that of POL2RA and Ki67. Legend as in Fig. 4 (C and D). Data of DYNC1H1 are from 176 particles.